Complex ventral hernia repair with a human acellular dermal matrix
Identifieur interne : 002C25 ( Main/Exploration ); précédent : 002C24; suivant : 002C26Complex ventral hernia repair with a human acellular dermal matrix
Auteurs : J. S. Roth [États-Unis] ; C. Brathwaite [États-Unis] ; K. Hacker [États-Unis] ; K. Fisher [États-Unis] ; J. King [États-Unis]Source :
- Hernia [ 1265-4906 ] ; 2014.
Abstract
The ideal approach to complex ventral hernia repair is frequently debated. Differences in processing techniques among biologic materials may impact hernia repair outcomes. This study evaluates the outcomes of hernia repair with a terminally sterilized human acellular dermal matrix (TS-HADM) (AlloMax® Surgical Graft, by C. R. Bard/Davol, Inc., Warwick, RI, USA) treated with low-dose gamma irradiation.
A single-arm multi-center retrospective observational study of patients undergoing hernia repair with TS-HADM was performed. Data analyses were exploratory only; no formal hypothesis testing was pre-specified.
Seventy-eight patients (43F, 35M) underwent incisional hernia repair with a TS-HADM. Mean follow-up was 20.5 months. Preoperative characteristics include age of 56.6 ± 11.1 years, BMI 36.7 ± 9.9 kg/m2, and mean hernia defect size 187 cm2. Sixty-five patients underwent component separation technique (CST) with a reinforcing graft. Overall, 21.8 % developed recurrences. Recurrences occurred in 15 % of patients repaired with CST. Major wound complications occurred in 31 % of patients overall. Based upon CDC surgical wound classification, major wound complications were seen in 26, 40, 56, and 50 % of Class 1, 2, 3, and 4 wounds, respectively. No grafts required removal.
Hernia recurrences are not uncommon following complex abdominal wall reconstruction. Improved outcomes are seen when a TS-HADM is utilized as reinforcement to primary fascial closure.
Url:
DOI: 10.1007/s10029-014-1245-5
PubMed: 24728767
PubMed Central: 4372681
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Complex ventral hernia repair with a human acellular dermal matrix</title><author><name sortKey="Roth, J S" sort="Roth, J S" uniqKey="Roth J" first="J. S." last="Roth">J. S. Roth</name><affiliation wicri:level="2"><nlm:aff id="Aff1">Department of Surgery, University of Kentucky College of Medicine, 800 Rose Street, C-226 UKMC, Lexington, KY 40536 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Kentucky</region></placeName><wicri:cityArea>Department of Surgery, University of Kentucky College of Medicine, 800 Rose Street, C-226 UKMC, Lexington</wicri:cityArea></affiliation></author><author><name sortKey="Brathwaite, C" sort="Brathwaite, C" uniqKey="Brathwaite C" first="C." last="Brathwaite">C. Brathwaite</name><affiliation wicri:level="2"><nlm:aff id="Aff2">Winthrop University Hospital, Mineola, NY USA</nlm:aff><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Winthrop University Hospital, Mineola</wicri:cityArea></affiliation></author><author><name sortKey="Hacker, K" sort="Hacker, K" uniqKey="Hacker K" first="K." last="Hacker">K. Hacker</name><affiliation wicri:level="2"><nlm:aff id="Aff3">Benrus Surgical Associates Inc., St. Peters, MO USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Benrus Surgical Associates Inc., St. Peters</wicri:cityArea></affiliation></author><author><name sortKey="Fisher, K" sort="Fisher, K" uniqKey="Fisher K" first="K." last="Fisher">K. Fisher</name><affiliation wicri:level="2"><nlm:aff id="Aff4">St. Francis Hospital, Inc., Tulsa, OK USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Oklahoma</region></placeName><wicri:cityArea>St. Francis Hospital, Inc., Tulsa</wicri:cityArea></affiliation></author><author><name sortKey="King, J" sort="King, J" uniqKey="King J" first="J." last="King">J. King</name><affiliation wicri:level="2"><nlm:aff id="Aff4">St. Francis Hospital, Inc., Tulsa, OK USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Oklahoma</region></placeName><wicri:cityArea>St. Francis Hospital, Inc., Tulsa</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24728767</idno><idno type="pmc">4372681</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372681</idno><idno type="RBID">PMC:4372681</idno><idno type="doi">10.1007/s10029-014-1245-5</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000D38</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000D38</idno><idno type="wicri:Area/Pmc/Curation">000D37</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000D37</idno><idno type="wicri:Area/Pmc/Checkpoint">001C62</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001C62</idno><idno type="wicri:Area/Ncbi/Merge">006568</idno><idno type="wicri:Area/Ncbi/Curation">006568</idno><idno type="wicri:Area/Ncbi/Checkpoint">006568</idno><idno type="wicri:doubleKey">1265-4906:2014:Roth J:complex:ventral:hernia</idno><idno type="wicri:Area/Main/Merge">002C29</idno><idno type="wicri:Area/Main/Curation">002C25</idno><idno type="wicri:Area/Main/Exploration">002C25</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Complex ventral hernia repair with a human acellular dermal matrix</title><author><name sortKey="Roth, J S" sort="Roth, J S" uniqKey="Roth J" first="J. S." last="Roth">J. S. Roth</name><affiliation wicri:level="2"><nlm:aff id="Aff1">Department of Surgery, University of Kentucky College of Medicine, 800 Rose Street, C-226 UKMC, Lexington, KY 40536 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Kentucky</region></placeName><wicri:cityArea>Department of Surgery, University of Kentucky College of Medicine, 800 Rose Street, C-226 UKMC, Lexington</wicri:cityArea></affiliation></author><author><name sortKey="Brathwaite, C" sort="Brathwaite, C" uniqKey="Brathwaite C" first="C." last="Brathwaite">C. Brathwaite</name><affiliation wicri:level="2"><nlm:aff id="Aff2">Winthrop University Hospital, Mineola, NY USA</nlm:aff><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Winthrop University Hospital, Mineola</wicri:cityArea></affiliation></author><author><name sortKey="Hacker, K" sort="Hacker, K" uniqKey="Hacker K" first="K." last="Hacker">K. Hacker</name><affiliation wicri:level="2"><nlm:aff id="Aff3">Benrus Surgical Associates Inc., St. Peters, MO USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Benrus Surgical Associates Inc., St. Peters</wicri:cityArea></affiliation></author><author><name sortKey="Fisher, K" sort="Fisher, K" uniqKey="Fisher K" first="K." last="Fisher">K. Fisher</name><affiliation wicri:level="2"><nlm:aff id="Aff4">St. Francis Hospital, Inc., Tulsa, OK USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Oklahoma</region></placeName><wicri:cityArea>St. Francis Hospital, Inc., Tulsa</wicri:cityArea></affiliation></author><author><name sortKey="King, J" sort="King, J" uniqKey="King J" first="J." last="King">J. King</name><affiliation wicri:level="2"><nlm:aff id="Aff4">St. Francis Hospital, Inc., Tulsa, OK USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Oklahoma</region></placeName><wicri:cityArea>St. Francis Hospital, Inc., Tulsa</wicri:cityArea></affiliation></author></analytic><series><title level="j">Hernia</title><idno type="ISSN">1265-4906</idno><idno type="eISSN">1248-9204</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Purpose</title><p>The ideal approach to complex ventral hernia repair is frequently debated. Differences in processing techniques among biologic materials may impact hernia repair outcomes. This study evaluates the outcomes of hernia repair with a terminally sterilized human acellular dermal matrix (TS-HADM) (AlloMax<sup>®</sup> Surgical Graft, by C. R. Bard/Davol, Inc., Warwick, RI, USA) treated with low-dose gamma irradiation.</p></sec><sec><title>Methods</title><p>A single-arm multi-center retrospective observational study of patients undergoing hernia repair with TS-HADM was performed. Data analyses were exploratory only; no formal hypothesis testing was pre-specified.</p></sec><sec><title>Results</title><p>Seventy-eight patients (43F, 35M) underwent incisional hernia repair with a TS-HADM. Mean follow-up was 20.5 months. Preoperative characteristics include age of 56.6 ± 11.1 years, BMI 36.7 ± 9.9 kg/m<sup>2</sup>, and mean hernia defect size 187 cm<sup>2</sup>. Sixty-five patients underwent component separation technique (CST) with a reinforcing graft. Overall, 21.8 % developed recurrences. Recurrences occurred in 15 % of patients repaired with CST. Major wound complications occurred in 31 % of patients overall. Based upon CDC surgical wound classification, major wound complications were seen in 26, 40, 56, and 50 % of Class 1, 2, 3, and 4 wounds, respectively. No grafts required removal.</p></sec><sec><title>Conclusions</title><p>Hernia recurrences are not uncommon following complex abdominal wall reconstruction. 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S." last="Roth">J. S. Roth</name></region><name sortKey="Brathwaite, C" sort="Brathwaite, C" uniqKey="Brathwaite C" first="C." last="Brathwaite">C. Brathwaite</name><name sortKey="Fisher, K" sort="Fisher, K" uniqKey="Fisher K" first="K." last="Fisher">K. Fisher</name><name sortKey="Hacker, K" sort="Hacker, K" uniqKey="Hacker K" first="K." last="Hacker">K. Hacker</name><name sortKey="King, J" sort="King, J" uniqKey="King J" first="J." last="King">J. King</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
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Ou
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Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4372681
|texte= Complex ventral hernia repair with a human acellular dermal matrix
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24728767" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
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